What Exactly is GDF-8 (Myostatin):
A myokine called myostatin (also called growth differentiation factor 8 or GDF-8) inhibits muscle cell growth and differentiation by interfering with the autocrine functions of myocytes, which produce and release the protein. The MSTN gene is responsible for encoding this protein in humans. In addition, the TGF beta protein family includes myostatin, a secreted growth differentiation factor.
Participants with increased muscle mass have lower myostatin levels or have been treated with a substance that inhibits myostatin function. In addition, individuals with genetic variations in both copies of the myostatin gene have significantly more muscle mass and are more powerful than the general population. Thus, studies on myostatin have the potential to uncover new treatments for diseases like muscular dystrophy, which cause the body to break down its muscle.
Due to an increased number of muscle fibres, animals like certain breeds of bulls have an extremely lean, hyper-sculpted, ultra-muscular physique because they produce less myostatin than other cow breeds.
GDF-8 works by preventing myostatin from being activated so it can’t bind to its receptors, which is how it works.
When myostatin binds to these receptors, they usually shut down muscle growth, but muscle growth is unhindered because GDF-8 prevents the binding. According to research, when myostatin is absent, muscle mass increases significantly in both people and animals. Myostatin deficiency has also been linked to increased bone mineral density in mice. In addition, gains in muscle and bone restoration were seen in animal studies using GDF-8, suggesting the peptide could be used to restore damaged muscle and bone tissue.
Duchenne’s muscular dystrophy, which causes progressive muscle atrophy, is being studied as a treatment option using the peptide. In addition, further research is being conducted on the peptide after the study results showed it to be a potential pharmacological strategy for treating diseases associated with muscle wasting.
Finally, a recent study in mice found that overexpressing the myostatin propeptide blocked myostatin signalling and resulted in remarkable muscle growth.
Another finding from the study showed that the peptide-induced muscle growth also showed that the muscle could generate average amounts of force.
Mole Weight: 25.0 kDa
Unit Quantity: 1 Vial
Appearance: White Powder
Peptide Purity: >99%