AOD-9604 For Sale

Description

What is AOD-9604 Peptide?

AOD-9604 is a synthetic peptide fragment derived from the C-terminal region of human growth hormone (hGH) corresponding to amino acids 176–191. Researchers developed this fragment to reproduce the lipolytic activity associated with growth hormone while avoiding the broader growth-promoting pathways of the full hormone.

Studies show that this peptide fragment stimulates lipolysis and inhibits lipogenesis in adipose tissue, processes that regulate body fat and fatty acid metabolism. Experimental animal studies report increased fat oxidation and reduced fat accumulation when researchers investigate this fragment in obesity models.

Because of these properties, suppliers provide AOD-9604 for sale as a synthetic peptide fragment for laboratory research use, where researchers study its role in fat metabolism, metabolic processes, and body weight regulation.

How Does AOD-9604 Work?

Research shows that AOD-9604 acts on lipid metabolism in adipose tissue by increasing fat-breaking activity in fat cells. Experimental studies report that the peptide stimulates lipolysis, increasing the breakdown of stored triglycerides into free fatty acids and glycerol in adipose tissue.

Studies also report that the peptide fragment inhibits lipogenesis, the metabolic process that forms and stores new fat in adipose tissue.

Mechanistic research indicates that AOD-9604 can increase lipolytic sensitivity in adipose tissue by interacting with β3-adrenergic signaling pathways, thereby influencing lipid metabolism and fat oxidation in experimental models.

Experimental findings further show that AOD-9604 does not interact with the human growth hormone receptor, allowing metabolic activity to occur without activating the growth-related signaling pathways associated with full human growth hormone.

Source: PubChem

Potential Benefits of AOD-9604 Peptide

• Lipolysis Activation: Studies report that AOD-9604 treatment increases lipolytic activity in adipose tissue, promoting the breakdown of stored fat.
• Fat Oxidation: Experimental research shows that AOD 9604 increases fat oxidation and lipid metabolism in animal models following treatment.
• Body Fat Reduction: Research in obese mice reports that AOD-9604 reduces body weight gain and body fat accumulation after chronic administration.
• Cartilage Regeneration: Pre clinical osteoarthritis models show that intra-articular AOD-9604 injections enhance cartilage regeneration and improve joint tissue structure.
• Metabolic Regulation: Studies indicate that AOD-9604 influences lipid metabolism pathways associated with fat processing and metabolic activity.
• Adipose Tissue Metabolism Regulation: Research reports that AOD-9604 increases lipolytic sensitivity in fat cells through β3-adrenergic receptor pathways that regulate fat metabolism.

My Peptides offers high-quality AOD-9604 for sale for laboratory research use only, not for human consumption.

Does AOD-9604 Have Any Side Effects?

Research on the growth hormone fragment AOD-9604 reports no significant adverse metabolic effects during experimental studies. Investigations show that treatment with the peptide does not impair insulin sensitivity or glucose metabolism, unlike full human growth hormone.

Safety evaluations also report that AOD-9604 does not increase circulating IGF-1 levels or trigger antibody formation, indicating that the peptide does not activate the growth-related pathways associated with full human growth hormone.

Published data further show that experimental treatment with AOD-9604 did not produce serious adverse events, and studies describe the compound as generally well tolerated in controlled investigations.

Because responses to experimental compounds can vary, researchers evaluate this peptide under controlled laboratory conditions. My Peptides offers high-quality AOD-9604 for sale for laboratory research use only, not for human consumption.

AOD-9604 Specifications

Molecular Formula: C78H123N23O23S2

Molar weight: 1815.1 g/mol

Appearance: White Powder

Peptide Purity: >99%

Discover premium quality AOD-9604 For Sale from My Peptides. Our AOD-9604 Peptide Vials are guaranteed 99% purity and are available in 2mg, 5mg, and 10mg for research. Buy AOD-9606 ONLINE today!

Scientific Research

[1] Misra M. Obesity pharmacotherapy: current perspectives and future directions. Curr Cardiol Rev. 2013 Feb 1;9(1):33-54.

[2] Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. Endocrinology. 2001 Dec;142(12):5182-9.

[3] Valentino MA, Lin JE, Waldman SA. Central and peripheral molecular targets for antiobesity pharmacotherapy. Clin Pharmacol Ther. 2010 Jun;87(6):652-62.

[4] Mao R, Zhao Q, Lu H, Yang N, Li Y, Teng D, Hao Y, Gu X, Wang J. The Marine Antimicrobial Peptide AOD with Intact Disulfide Bonds Has Remarkable Antibacterial and Anti-Biofilm Activity. Mar Drugs. 2024 Oct 8;22(10):463.

[5] Ng FM, Sun J, Sharma L, Libinaka R, Jiang WJ, Gianello R. Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone. Horm Res. 2000;53(6):274-8.

[6] Liao HJ, Chen HT, Chang CH. Peptides for Targeting Chondrogenic Induction and Cartilage Regeneration in Osteoarthritis. Cartilage. 2024 Sep 18:19476035241276406.

Frequently Asked Questions

Is AOD-9604 FDA-approved?

AOD-9604 is not approved by the U.S. Food and Drug Administration. Researchers originally developed this growth hormone fragment as a potential anti-obesity therapy, but development did not lead to regulatory approval for clinical use. Studies instead examine the peptide mainly in experimental settings focused on fat metabolism and adipose tissue activity rather than as an approved medical treatment.

Does AOD-9604 help with fat metabolism?

Research shows that this growth hormone fragment acts on lipid metabolism in adipose tissue. Experimental studies report increased lipolytic activity and changes in fat processing during treatment in animal models. Investigators observed greater breakdown of stored fat and altered lipid metabolism compared with untreated controls, indicating that the peptide can influence pathways involved in fat metabolism.

Is AOD-9604 a growth hormone?

AOD-9604 is not a full growth hormone. Researchers created it as a synthetic fragment of human growth hormone derived from the C-terminal region. Studies show that this fragment mimics specific metabolic actions related to fat metabolism while avoiding the broader growth-promoting effects, such as organ growth or cellular proliferation, normally triggered by intact human growth hormone.

What is the difference between AOD-9604 and HGH fragment 176-191?

Both originate from the same region of the human growth hormone gene. While HGH fragment 176-191 represents the natural sequence, AOD-9604 is a synthetic analogue (often including a tyrosine at the N-terminal) designed for enhanced stability in metabolic research. Studies describe the analogue as targeting fat-metabolism pathways and lipolysis without activating growth hormone receptor signaling that drives systemic growth.

Does AOD-9604 affect insulin or IGF-1 levels?

Studies report that the peptide fragment does not interact with the growth hormone receptor and does not trigger the hormonal responses typically seen with full growth hormone. Experimental research also shows that treatment did not impair insulin sensitivity or glucose regulation in animal models. This indicates minimal influence on insulin-related metabolic pathways compared to full-length hGH.

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DISCLAIMER: All products sold by My Peptides are strictly intended for research and laboratory use only. These items are not designed for human or animal use or consumption. They are not classified as drugs, food, cosmetics, or medicinal products and must not be mislabeled or misused as such. By purchasing from our website, buyers acknowledge and accept all risks associated with handling these materials. The information and articles provided on this website are purely for educational and informational purposes. Handling and usage of these products should be carried out exclusively by qualified professionals.