Tesamorelin

A trans-3-hexenoic acid group and 44 amino acids from GHRH (growth hormone-releasing hormone) make up the Tesamorelin peptide. Studies have shown benefits for lipodystrophy use. Research also suggests that weight loss, heart disease, and dementia can all be helped with Tesamorelin. Scientists are currently delving deep into the subject to uncover more possible health benefits.

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Description

What Exactly is Tesamorelin:

In men and women, tesamorelin can raise IGF-1 levels by acting as a growth hormone-releasing analogue. Similar to GHRH in potency, this growth hormone could connect and stimulate GHRH receptors.

This human growth hormone also has numerous advantages, including the following:

  • Effects of nootropic peptides
  • Lowering cholesterol and triglycerides

Research has shown visceral fat tissue (VAT), CIMT (carotid intima-media thickness) and C-reactive protein all decreased with the use of tesamorelin (CRP.) Despite this, studies have shown other pituitary hormones, and body mechanisms are not significantly affected by this growth hormone.

Research has also found Tesamorelin can help the cognitive function of the elderly and patients with mild cognitive impairment who have a heightened risk of Alzheimer’s disease.


What is Tesamorelin Known For?

Tesamorelin has been researched and is known for:

Reduced body weight

Tesamorelin has been shown in clinical trials to have potent weight loss effects, including reducing abdominal fat. As a result, Tesamorelin supplements are popular among those looking to lose weight because of their fat-burning properties.

Increased muscle mass

Tesamorelin research has been shown to increase lean muscle mass. Tesamorelin aids in tissue growth and repair by raising levels of growth hormone in the body. It’s a popular protein among bodybuilders. However, you can’t buy it for those purposes just yet because it’s illegal. It’s currently available only to HIV patients.

Damage to the Peripheral Nervous System

Nerve damage in the periphery can be caused by trauma, diabetes, or even surgery. The most common side effect of this disease is severely impaired motor and sensory function. On the other hand, peripheral nerve damage has a minor treatment window because nerve cells are challenging to regrow.

Studies have shown that the growth hormone manipulation therapy known as tesamorelin therapy can help heal peripheral nerve injuries and speed up recovery time.

HIV

Researchers have found an increased risk of metabolic and hormonal problems, such as hypogonadism, in patients taking HAART. For this reason, one-third of HIV patients have a GH deficiency due to changes in the pituitary gland caused by infection. There is a treatment for this deficiency called tesamorelin, which has been shown to be both effective and safe.

To be certified as a potential HIV medicine, researchers must conduct more clinical trials. However, the results of the research done thus far are encouraging and look extremely promising.

HIV-associated Lipodystrophy

According to research, lipodystrophy is a condition in which the body cannot produce or maintain healthy fat tissue. As a result, fat builds up in the abdomen and other troublesome places. Scientists have no idea what causes lipodystrophy, but they know that tesamorelin peptide may be a cure.

Tesamorelin was approved as a treatment for HIV-associated lipodystrophy because research suggests it is four times more effective than all other combined therapies.

Heart disease

Because of abnormal fat deposition, individuals living with HIV have an increased risk of cardiovascular disease (CVD). Therefore, medical professionals believe that preventing CVD should be a top priority for HIV-positive people.

Tesamorelin studies have been shown in HIV patients to lower triglyceride, non-HDL-C, and cholesterol levels. In addition, using tesamorelin reduces visceral adipose tissue when triglyceride levels are reduced. Tesamorelin lowers the risk of cardiovascular disease by reducing inflammation.

Dementia

Tesamorelin may help patients with mild cognitive impairment by improving their memory, according to new research. In addition, Tesamorelin peptide may help slow the progression of dementia by improving cognition in the early stages.

Tesamorelin appears to hold promise as a treatment for dementia, but more research is needed before it can be widely available.


Studies:

https://pubmed.ncbi.nlm.nih.gov/20554713/

https://jamanetwork.com/journals/jama/fullarticle/1889139


Effects:

Research has shown Tesamorelin has several advantages, which are detailed below:

  • HGH production is now more abundant (human growth hormone)
  • Affects insulin growth factor 1 without affecting blood sugar levels
  • Triglyceride levels are down.
  • Tissue Loss in the Abdomen and Viscera (VAT)
  • Slightly smaller carotid intima/media (cIMT)
  • Age-related improvements in cognition in adults

Side Effects:

Studies suggest Tesamorelin may cause the following side effects, which are listed below:

  • Reactions due to allergy
  • Chest tightness or pain
  • Increased intake of food or fluids
  • Feeling of lethargy and weakness.
  • Palpitations
  • Dejected state of mind
  • Pain in the muscles
  • Nausea
  • Vomiting
  • Pain
  • Bruising or itching at the injection site
  • The sensation of having pins and needles in your fingers and toes
  • Ankle, foot, or hand swelling

Formula: C221H366N72O67S

Molar mass: 5135.77

Sequence: trans-hexenoyl-acid-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn- Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-LeuGln-Asp-Ile-Met-Ser-Arg-Gln- Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2

Unit Size:

Unit Quantity: 1 Vial

Appearance: White Powder

Peptide Purity: >99%

Additional information

Size

2mg, 5mg, 10mg

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